University Publications

Amino acid complexes of Ni2+ with L-Leucine and mixed amino acid of Cysteine + Leucine have been synthesized and characterized in the present study. Characterization was carried out using powder X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), UV/Vis-spectroscopy, Conductivity measurement, Thermo gravimetric analysis (TGA) and Energy dispersive X-ray (EDX). The ligands with Ni+2ion have been found to act as bidentate chelating agents coordinating through carboxyl group (COO-) and amino group (NH2). The antibacterial activity of amino acid complexes was evaluated against four bacteria strains, two gram positive (Staphylococcus aureus and Enterococcus feacalis), and two gram negative (Escherichia coli and Klebsiella pneumonia). The Ni+2complexes were found to have a good degree of inhibitory effect against bacteria.