University Publications

This study was designed to determine the antimicrobial sensitivity patterns of bacterial isolates from patients who visited different hospitals and medical laboratories in Thamar City, Yemen. 135 specimens collected from various clinical samples: blood (62), urine (38), stool (35) were analyzed and the organisms were identified using colonial morphology, gram staining, appropriate biochemical test and API20E. The identified organisms include Salmonella typhi, S. paratyphi, Escherichia coli, Klebsiella pneumonia, Shigellae sp Salmonella sp., Citrbacteir freundi, Enterobacter sp. Antibiotics susceptibility studies showed that S. typhi isolates were highly resistant to lincomycin, tetracycline and most were resistant to rifampicin and nalidixic acid. Intermediate resistance was observed to ciprofloxacin and Norfloxacin and all were susceptible to amoxicillin, doxycycline, streptomycin, gentamycin and ampicillin. S. paratyphi isolates showed resistance to lincomycin, tetracycline, streptomycin and nalidixic acid but susceptible to amoxicillin, doxycycline and gentamycin. E. coli isolates showed high resistance to ampicillin, erythromycin, lincomycin, amoxicillin and rifampicin and ciprofloxacin, tetracycline, doxycycline, streptomycin, gentamycin and nalidixic acid. K. pneumoniae isolates showed high resistance to erythromycin, lincomycin, rifampicin, streptomycin, amoxicillin and ciprofloxacin but moderate resistance to tetracycline, nalidixic acid and doxycycline. Shigellae species isolates were resistant to erythromycin, lincomycin, rifampicin and gentamycin and tetracycline, ampicillin, amoxicillin but less resistant to doxycycline. Most of Shigellae species isolates were susceptible to norfloxacin and ciprofloxacin. Non-typhoid Salmonella species isolates were multi-drug resistant to the antibiotics tested. Drug resistance was encountered in most of studied isolates was attributed to their prevailing usage and abuse.