This study aimed to synthesize two types of phenolic Mannich bases and to calculate some of their optical properties. A general synthesis strategy was adopted: the active hydrogen compound, formalin and a secondary amine were mixed in ethanol for different intervals to afford the final products. In this way, the following Mannich bases were synthesized (1-[(piperidin-1-yl) methyl] naphthalen-2-ol) and (3-(diethyl amino) naphthalen-2-yl acetate). The optical properties. e.g. the absorption, absorption coefficient extinction coefficient, refractive index and energy band gap were calculated for ((1-[(piperidin-1-yl) methyl] naphthalen-2-ol) and (3-(diethyl amino) naphthalen-2-yl acetate)) samples by using spectrophotometer measurements of the transmittance and reflectance at normal incidence in the spectral range 200–500 nm. The two Mannich bases illustrated different values for the calculated parameters (absorption, absorption coefficient, extinction coefficient, refractive index and energy band gap). The differences are related to the nature of Mannich base.