Background: haemorrhage is the third highest direct cause of maternal death. Haemorrhage emerges as the major cause of severe maternal morbidity in almost all ‘near miss’ audits in both developed and developing countries. In Sudan, more than 1 in 3 women who deliver suffer from prolonged labour, and 1 in 4 women experiences excessive bleeding. Two thirds of maternal death cases reviewed indicates delay in women’s decision to seek care and a delay in identifying and reaching medical facility. One third of deaths well relate to not receiving adequate care once hospitalized. Aim: The present study aimed to measure the knowledge of nurses and midwives in Khartoum state regarding the management of primary postpartum haemorrhage. Method:A descriptive cross-sectional, hospital based-study, the current study was conducted at specialized maternity government hospitals in Khartoum state. The sample of the study consisted of 81nursesand midwives selected using the simple random sampling method. The data were collected by a questionnaire and were analyzed by the Statistical Packages for Social Sciences (SPSS), version 25, and then the data were presented in form of simple frequency tables and cross-tabulations to explore the relationship between variables. P-value ≤ 0.05 was considered statistically significant. Ethical approval was obtained from ethical committees and administrative authorities of hospitals, and verbal consent was obtained from the respondents enrolled in the sample of the study. Results:The findings illustrated that almost halfof the nurses and midwives (49.4%) had fair knowledge about obstetric emergency during labor.Slightly above half of the studyparticipants(55.6%) had good knowledge regarding the role of midwives in obstetric emergency during labor.Conclusion: The study concluded that nurses and midwives had fair knowledge about obstetric emergency during laborand had good knowledge regarding the role of midwives in obstetric emergency during labor. Key words:Emergency obstetric care, Knowledge, Midwives, Primary Postpartum Haemorrhage